Mexico City to Guatemala


Mexico City, Mexico
Mexico City, Baja California, Mexico
Oaxaca, Mexico
From Dec 7, 2026 to Jan 22, 2027 (Flexible)

Trip Details

6-week backpacking adventure: Mexico, Belize & Guatemala

42 days · 3 countries · Backpacking · ADO buses, shuttles, ferries and selected flights

I'd organize this as a one-way journey through southern Mexico, the Caribbean coast, Belize and Guatemala, finishing with a full week at beautiful Lake Atitlán.

The idea is to combine Mayan history, colonial cities, beaches, local culture, markets and nature, without spending too much time moving from one destination to another.

Pronóstico del clima en Oaxaca, Oaxaca hoy 8 de febrero de 2026
Tropical beach setting on Isla Holbox, Mexico
San Pedro vs San Marcos vs Panajachel: Which Lake Atitlán Town is Right for You? | Sababa Resort

Recommended six-week itinerary

Week 1

7 days

Mexico City & Oaxaca

Mexico City for museums, Teotihuacán and historic neighborhoods, then Oaxaca for Zapotec ruins, food, mezcal and indigenous culture.

Week 2

7 days

Playa del Carmen & Isla Holbox

Fly to Cancún, then use ADO buses and ferries. Visit cenotes, Caribbean beaches and the laid-back island of Holbox.

Week 3

7 days

Tulum, Bacalar & Belize

Travel south via Tulum and Bacalar into Belize, visiting Caye Caulker and Belize's Caribbean coast.

Week 4

7 days

Belize & Tikal, Guatemala

Visit San Ignacio, Maya archaeological sites and jungle landscapes before crossing into Guatemala to explore Tikal and Flores.

Week 5

7 days

Antigua Guatemala & highlands

Travel to Antigua for Spanish colonial architecture, volcano views, local coffee culture and optional hiking.

Week 6

7 days

Lake Atitlán

Spend the final week exploring lakeside villages, Mayan communities, markets and hiking trails, with time to relax.

Route map

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Alle Gruppen
Mexico CityGovernment office
Oaxaca4,3•City parkGeöffnet
Playa del Carmen4,4•Beach
Isla Holbox4,0•Island
Tulum4,5•Archaeological siteGeöffnet
Bacalar4,8•Lagoon
Caye Caulker4,5•Island
San Ignacio4,2•MarketGeöffnet
Flores4,7•Villa
Tikal4,8•National parkGeöffnet
Antigua4,4•ParkGeöffnet
Lake Atitlan4,7•Tourist attractionGeöffnet

Route overview, not a continuous driving route. Some sections require flights, ferries or connecting shuttles.

Cultural highlights I would prioritize

Aerial viewMonte Alban, a large pre-Columbian archaeological site, Santa Cruz Xoxocotlan Municipality, Oaxaca State.  UNESCO World Heritage

Monte Albán — Mexico

Ancient Zapotec ceremonial center overlooking Oaxaca. Combine it with Oaxaca's traditional markets, textiles and regional cuisine.

Tikal Great Plaza and Grand Jaguar Temple, Guatemala

Tikal — Guatemala

One of the most impressive Maya archaeological sites in Central America, with towering temples surrounded by jungle.

Highlights of Guatemala - Tailor-made by Steppes Travel

Antigua Guatemala

Colonial streets, historic churches, coffee plantations and volcanoes. A great place for walking and Spanish classes.

File:Chichicastenango market.jpg - Wikimedia Commons

Chichicastenango Market

A colorful traditional highland market, best visited on Thursday or Sunday, with Maya textiles, handicrafts and local traditions.

Your final week: Lake Atitlán

Sababa San Pedro La Laguna? Discover Sababa Resort in Guatemala! | Sababa Resort
Le lac Atitlán au Guatemala
Colorful town houses in the indigenous mountain village along lake Atitlan, Santa Cruz La Laguna, Guatemala
9

I'd spend four nights in San Pedro La Laguna or San Juan La Laguna and three nights in Santa Cruz La Laguna or Panajachel.

Use the public boats to explore different villages, visit Maya weaving cooperatives, take a cooking or Spanish lesson, hike to Indian Nose for sunrise and spend a couple of days relaxing by the lake.

This is a much nicer finish than rushing between additional cities.

Transportation plan

Route

Transport

Approximate time

Mexico City → Oaxaca

ADO bus

6–7 hrs

Oaxaca → Cancún

Flight

2 hrs 10 min

Cancún → Playa del Carmen

ADO bus

1–1.5 hrs

Playa → Holbox

Bus to Chiquilá + ferry

3–4 hrs

Holbox → Tulum

Ferry + connecting buses

4–6 hrs

Tulum → Bacalar

ADO bus

2.5–3.5 hrs

Bacalar → Belize City

Bus/shuttle via Chetumal

4–6 hrs

Belize City → Caye Caulker

Water taxi

45–60 min

Caye Caulker → San Ignacio

Ferry + bus

3–5 hrs

San Ignacio → Flores

Cross-border shuttle

3–5 hrs

Flores → Antigua

Flight via Guatemala City + shuttle

Most of a day

Antigua → Lake Atitlán

Shuttle

2.5–4 hrs

ADO serves the main Mexican corridors, and direct Oaxaca–Cancún flights are currently listed. Cross-border Belize services are less predictable, so I would verify that leg shortly before travel.

ADO Blog - blog.ado.com.mx
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Estimated backpacking budget

Per person · 42 days · US dollars · Planning estimates, not live quotes

Hostels / budgetPrivate rooms

Estimated total

$2850–$4350

Average per day

$68–$104

Accommodation & meals

$1400–$2100

Ground transport, ferries & regional flights

$800–$1200

Activities & cultural visits

$650–$1050

Excludes flights to Mexico and home from Guatemala, insurance and major unexpected expenses.

My preference would be private rooms in small guesthouses rather than dormitories. You still get the backpacking experience and opportunities to meet people, but with more comfort and privacy.


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